Case reports from Asia: you Can meet the Coronavirus Healed again?
Multiple messages to each individual patient, released as recovered from the hospital and a few days later again positive for the Coronavirus were tested came from Asia.
Recently there was a communication from the South Korean CDC KCDC to 91 such cases. The persons Concerned were not immune and to put right again?
Or the pathogen, such as, for example, herpes viruses do came back after a resting stage?
Probability of infection with Coronavirus is low
Even if the last security in the absence of large studies is that it is Very likely a different, quite a harmless phenomenon, flare up is the main cause for the supposed back.
“In the decay phase of the disease, the remaining quantities of Virus over time, sometimes under the detection limit of the PCR Tests,“ explain Melanie Brinkmann of Technical University of Braunschweig and Friedemann Weber of the University of Giessen in a joint statement.
“In this Phase, the Test works rather randomly.“
The Berlin-based virologist Christian Drosten of the Charité emphasized that the causative agent could just be the end of the disease temporarily undetectable, and in between, some days not.
“The Virus is there all the time, but the Test can’t capture,“ he said in the NDR Podcast.
Drosten uses to illustrate a vivid picture: gold fish in a paddling pool. Someone take with connected eyes it with a bucket of a sample that had a gold fish as an image for a virus particle, and sometimes not.
At the end of the disease, the viral load was still low, in comparison, therefore, is less and less of the gold fish in the basin.
Negative Tests despite a virus
Thus, the probability to guess that a Test of the round will also negative, although there was still virus material in the patient. Especially in the case of smear samples from the neck, this is not surprising, says Drosten in the NDR Podcast.
In respiratory secretions and stool, the Virus is much longer easily detectable and, at least in some cases, are sacrificing the above-mentioned patients first, and Revenge later, lung secretion (high gehustetes Secretion) or chair has been tested.
“That is my explanation for this phenomenon,” says Drosten. Occasionally, Brinkmann and Weber may suggest a certain Re-flare up of the Virus play a role.
Something like latency – Hiding of the Virus in the cells of the body, and reactivation for example in Stress – as in the case of herpes virus, it will not give in the case of coronaviruses, however, stresses the Brinkmann.
The operation of the latency is extremely complicated, with the herpes virus could have it perfected in millions of years of Coevolution with humans.
Not entirely excluded, but very unlikely to be a direct Neuansteckung by experts.
In the case of the previously tested patient about ten to 14 days after the onset of symptoms, antibodies against Sars-CoV-2 in the blood are usually been shown to the convalescent people should, in principle, to protect at least some time in front of a new infection.
How well and for how long? “The can judge at the present time no one is safe,“ explained Brinkmann and Weber.
Residual virus is not transferable
But what does it mean for the risk of contagion, when Convalescent carry the Virus for a few days further in? The most important point here is that everywhere in the world, used in PCR Tests for the presence of not an activity of the virus.
To put it also in the case of remaining residues, since they showed only the presence of the Erbmoleküls RNA, explain Brinkmann and Weber. So, let’t see if the proven the Virus is still infectious or not.
According to current knowledge, the recovery of the virus detected material prosperity is infectious for others, it was very likely mostly dead, retired Material, says Drosten.
It’s already the first analyses. “We were never able to isolate infectious Virus.“
Deutsche Presse-Agentur (dpa)
*The contribution of “case reports from Asia: the Coronavirus Healed again to meet?” is published by FitForFun. Contact with the executives here.